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Chunk #7 — MATERIALS AND METHODS — Experimental Design

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Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol-Preferring (P) Rats.
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The effects of VAR on alcohol drinking were assessed during reaccess to alcohol following each of the 3 alcohol deprivation periods. Rats were treated with VAR or VEH for the first 5 consecutive days of each of the three reaccess cycles. The remaining days of each alcohol reaccess cycle were not accompanied by drug treatment, but alcohol access was maintained at 2 hours a day.