paperKB
coga / coga-kb
Help
Sign in

Chunk #8 — MATERIALS AND METHODS — Data Analysis

Source
Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol-Preferring (P) Rats.
Embedded
yes

Text

Alcohol and water intake during the 2-hr daily alcohol reaccess periods were analyzed using 2-way repeated measures (RM) analyses of variance (ANOVAs) (treatment x day, RM on day). When sphericity could not be assumed, as indicated by a significant Mauchly’s test (p<0.05), Greenhouse-Geisser was used to correct the degrees of freedom. Significant main effects and interactions were further analyzed using Dunnett’s pairwise multiple comparisons against a single mean (VEH). To assess the stability of alcohol intake prior to and following deprivation, alcohol intake during the last 5 days prior to onset of alcohol deprivation was compared with alcohol intake on day 1 of alcohol reaccess in the VEH group using a paired student’s t-test.