XheW and XZ designed this study and contributed to the paper writing. XC, XS, and XhuiW established Nrf2 silenced and over expressed HepG2 cell models, and participated in western blot assay and the paper writing. XL and YQ participated in the HepG2 cells viability assay and animal feeding. MH, WL, and IM conducted the experiment of liver pathology and real-time PCR assay.
