Chunk #38 — Discussion and conclusions

Source

High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2.

Embedded

yes

Text

In conclusion, our data give us a clue that HFD-induced hepatic 18-carbon FA accumulation up-regulates CYP2A5/2A6 via Nrf2 during hepatocellular steatosis. However, Nrf2 is not the only molecule that regulates the expression of CYP2A5/2A6.