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Chunk #16 — RESULTS — Distributions of 5-HTTLPR genotype across populations

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The serotonin transporter polymorphism (5-HTTLPR): allelic variation and links with depressive symptoms.
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The comparisons reveal striking differences in the distributions of 5-HTTLPR by race and ethnic group. Almost half of the SEBAS respondents (45%) are classified as homozygous for the S allele, a lower prevalence than those observed in the other East Asian studies (49–74%) and similar to Native American samples (42%), but much higher than in Caucasian samples from various countries (12–24%) and African Americans (7–17%). Conversely, the proportion with the L/L genotype in the SEBAS sample (8%) is substantially lower than in Caucasians (29–43%) and African Americans (45–56%), but is generally comparable to Native American (10–14%) and other East Asian samples (1–13%).