Chunk #4 — 2. Experimental Section

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Polygenic scores predict alcohol problems in an independent sample and show moderation by the environment.

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yes

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We drew upon two population-based samples in the present study. GWAS results from the Avon Longitudinal Study of Parents and Children (ALSPAC) [23] were used to create polygenic risk scores in the independent FinnTwin12 sample [24]. The samples and measures are described in greater detail below.