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Chunk #13 — Results

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Linkage analysis merging replicate phenotypes: an application to three quantitative phenotypes in two African samples.
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We carried out an Eigenstrat analysis [5] using all 24,487 SNPs from the unrelated individuals sample. We observed the expected separation between the broad geographic groups (data not shown). Given the debate surrounding Entine’s [6] controversial book that points out that virtually all the endurance marathon records are held by East Africans while virtually all the shorter speed records are held by West Africans, we were interested to see the degree of clustering between just the Luhya sample and the Yoruba sample (Figure 1). As can be seen, the Luhya sample is tightly clustered for the first three principal components, whereas the Yoruba sample is much more spread out. (By comparison, the two Chinese samples and the Japanese sample are virtually identical [data not shown].)