Asian and European studies and non-Asian studies (P = 1×10−28 and 1×10−6, respectively). In contrast, the European studies showed moderate evidence of association with an allelic P value of 0.0007. The Mexican studies showed weak association (P = 0.034) possibly due to limited sample size. In addition, significant association was also revealed in the combined Mexican Americans and African Americans (including the studies investigating the Cys allele), and the P values were 0.0001 and 4×10−15 for the allelic analysis and recessive model, respectively.
