Our results indicated that parental substance misuse largely failed to moderate the association between PTEs and adolescent drug use. Significant interactions were only observed for two drug use types. Adolescents reporting parent substance misuse were at higher risk for lifetime marijuana use associated with other PTEs (RR=1.63, CI: 1.28-2.07), compared to adolescents reporting no parent substance misuse (RR=1.38, CI: 1.00-1.90; pinteraction=.046). Adolescents reporting parent substance misuse were also at higher risk for use of other drugs associated with interpersonal PTEs (pinteraction=.02), any PTE (pinteraction=.02), and number of PTEs (pinteraction=.001), compared to adolescents not reporting parent substance misuse.
