Controlling for demographic covariates, exposure to any PTE before the age of 11 was associated with higher risk for lifetime use of marijuana (RR=1.50, CI: 1.33-1.69), cocaine (RR=2.78, CI: 1.95-3.97), nonmedical prescription drugs (RR=1.80, CI: 1.29-2.51), other drugs (RR=1.90, CI: 1.37-2.63), and multiple drugs (RR=1.74, CI: 1.37-2.20) (Table 2). Controlling for parent substance misuse attenuated these effect estimates; however, all remained statistically significant. There was evidence of a positive monotonic relationship for number of PTEs experienced and risk of marijuana, other drug, and polydrug use (Figure 1). Controlling for demographic covariates and parent substance misuse, any, one, two, and three or more childhood PTEs reported were all statistically associated with higher risk for marijuana and cocaine use.
