Ascertainment of incident type 2 diabetes involved a review of the existing EPIC datasets at each centre using multiple sources of evidence including self-report, linkage to primary care registers, secondary care registers, medication use (drug registers), hospital admissions and mortality data (online appendix; table ST1). Information from any follow-up visit or external evidence with a date later than the baseline visit was used. Cases in Denmark and Sweden were not ascertained by self-report, but identified via local and national diabetes and pharmaceutical registers and hence all ascertained cases were considered to be verified (online appendix; table ST1).