From Table 3a it can be seen that there were two major haplotypes of nearly equal frequency (denoted H1 and H2) and a minor (i.e., low frequency) haplotype (H3). Cases and controls had similar haplotype frequencies. The results of the logistic regression analysis where H2 (the most frequent haplotype) is the reference haplotype are presented in Table 4. Within the overall model there was an effect of sex (p < .0001) and trauma (p < .0001) such that males and trauma-exposed individuals were more likely to be alcohol dependent.
