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Chunk #20 — Results

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Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking.
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Daily ethanol intakes of the P rats were 1.5 to 2 g/kg/session over the 8 weeks of access (Fig. 1). Blood ethanol levels were not measured in the present study. However, intakes of 1.5 to 2 g/kg have previously been shown to produce blood alcohol concentrations greater than 80 mg% (Bell et al., 2005). Measures of intoxication following the 1-hr drinking periods were not assessed; in addition, measures of development of dependence and tolerance were not undertaken. There was no significant weight difference between the water and ethanol groups. Water intake during the ethanol access periods was negligible so that ethanol preference scores were > 99%.