(P=0.03) among individuals with the inversion compared with individuals without the inversion (Efron et al., 2003). At the time the De Silva et al. (2003) and Efron et al. (2003) manuscripts were published, the inversion breakpoints were described as being located in the 3p14 and 3q21 bands as determined by cytogenetic analysis using G-banding. The group later mapped the precise location of the inversion breakpoints and found that they occurred within intron 19 of the dedicator of cytokinesis 3 (DOCK3) and intron 13 of the solute carrier family 9 (sodium/hydrogen exchanger) isoform 9 (SLC9A9) at the p-arm and q-arm, respectively (De Silva et al., 2003). The true cytogenetic locations of DOCK3 and SLC9A9 are 3p21 and 3q24, respectively, and we believe the low resolution of the G-banding technique led to the discrepant cytogenetic positions in the original report. In addition to mapping the inversion breakpoints, De Silva et al. (2003) assessed the spatial expression patterns for both DOCK3 and SLC9A9 in the brain. They found that DOCK3 was expressed at the highest levels in the frontal, temporal, and occipital lobes, whereas SLC9A9 was expressed highest in the medulla and spinal cord (De Silva et al., 2003). Given these data, it
