(3) 2.6 (1.1–5.8) 3.6 (1.3–9.7) >1418 (6)19 (2) 4.3 (1.9–9.7) 4.4 (1.4–13) p-trend p = 0.0002 p = 0.002 Frequency of binge drinking ≤1/month27 (9)42 (5) 3.0 (1.5–5.9) 4.3 (1.8–10) 2–3/month13 (4)30 (3)2.0 (0.9–4.5) 3.0 (1.1–8.6) >3/month24 (8)45 (5) 2.4 (1.2–4.9) 3.0 (1.2–7.4) p-trend p = 0.02 p = 0.06Duration of binge drinking, years 1–512 (4)28 (3)2.1 (0.9–5.0)2.3 (0.8–6.8) 6–1013 (4)31 (4)1.7 (0.9–4.5) 2.9 (1.1–7.8) >1039 (13)60 (7) 2.9 (1.5–5.4) 3.7 (1.9–11) p-trend p = 0.001 p = 0.0006 CI, confidence interval; OR, odds ratioBold indicates that 95% confidence interval for point estimate did not cross 1, or p value < 0.05 aAdjusted for age (in 5-year group) bAdditionally adjusted for energy intake (kcal/day, men: quartiles, women: quartiles), body mass index (<25, 25.0–29.9, ≥30 kg/m2), race (white, black/African American, Asian/Pacific Islander, others), education (<high school, high school, 1–4 years college, graduate school), smoking (never smoker, former cigarette smoker who had quit smoking >15 years previously, former cigarette smoker who had quit smoking 1–15 years previously, current cigarette smoker or former cigarette smoker who had quit <1 year previously, pipe and/or cigar smoker), lifetime alcohol consumption, history of diabetes (yes, no), and physical activity (30-min moderate exercise each time: <1 month,
