al. [29] (n = 469, p-value = 7×10−4), Hassanein et al. [31] (n = 4,217, p-value = 3×10−4), and Hester et al. [32] (n = 4,992, p-value = 0.07) but not with four smaller AA studies (≤1000 AA subjects) [5], [18], [28], [38]. Consistent with our finding Hassanein et al. [31] also observed a significant association with rs9941349 and rs1558902 (n = 9,881, p-value = 4×10−6 and n = 4,217, p-value = 2×10−5, respectively), these SNPs have not been genotyped in other AA studies. However, to put these findings into context with other variants in this region a comprehensive evaluation of all variants is needed.
