Current findings highlight the importance of taking a developmental perspective and examining ethnic differences in developmental trajectories of adolescent alcohol abuse. The findings also indicate the value of incorporating biological information into developmental and intervention research. Our findings suggest that individual differences in the genome lead some individuals to be more malleable than their peers to intervention effects. More specifically, our findings suggest that the integration of genetics into prevention science raises the awareness of prevention researchers that individual genetic predispositions also play a crucial role in their responsiveness to intervention, and offer insights into the complex developmental mechanism underlying risk and resilience processes that could inform future intervention for refinement. Genetically informed RCTs could be incorporated into future intervention research, such as utilized in microtrials, to identify intervention components effective for individuals with different susceptibility (Brody et al. 2013; Howe et al. 2010).
