To enhance MR5 and MR6 data compatibility, MR6 scans were re-sampled into the same resolution and image size as MR5 scans so as to simulate similar amounts of partial volume effects in voxels that border two tissue types. To verify our ability to combine data from the 2 MR protocols, we have acquired both MR5 and MR6 scans on 60 patients (Ho, Andreasen, Ziebell, Pierson, & Magnotta, In Press). Brain volume differences between the two imaging sequences were small (Median percent difference=0.19%). Intra-class correlations were high across regions of interest (Median ICC=0.97). Hence, MR5 and MR6 data are compatible for combined statistical analyses.
