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Chunk #29 — Results — Biometric Model Fitting: Substance Use Disorder — Multivariate models

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Age at first use and later substance use disorder: Shared genetic and environmental pathways for nicotine, alcohol, and cannabis.
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The best-fitting model structure was the same in men and women: both common and specific family environmental influences could be constrained to zero (see Table 4b). Table S9 in supplemental materials displays the proportion of variation in substance use disorder attributable to common and substance-specific sources of genetic and environmental variance within the full CPM.