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Chunk #21 — DISCUSSION

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The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G × E effects.
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be a risk factor for AD relative to the H2/H2 diplotype; however, with trauma exposure carriers of the H1/H1 diplotype were found to be more resilient to the development of AD relative to H2/H2 carriers. A similar pattern of results emerged for the H1 haplotype in block 2, indicating that the relative risk of alcoholism was moderated by exposure to traumatic stress.