The Supplementary Note, Supplementary Tables 17–22 and 35–39, and Supplementary Figs. 10–11 and 16 provide further details and report the results of these and other bioinformatics analyses, including a transcriptome-wide analysis with Summary-based Mendelian Randomization (SMR)57, and an ascertainment of whether the lead SNPs and their LD partners (SNPs with an r2 > 0.6 with a lead SNP and no more than 250 kb from it) are protein-altering variants or are associated with cis-gene expression in distinct human tissues, among other analyses. The Supplementary Note also highlights the most important results of the bioinformatics analyses and summarizes the conclusions we derive from them.
