Chunk #15 — METHODS AND MATERIALS — Exploratory pathway and network analyses

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De Novo Damaging DNA Coding Mutations Are Associated With Obsessive-Compulsive Disorder and Overlap With Tourette's Disorder and Autism.

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Using the GeNets algorithm (https://apps.broadinstitute.org/genets), we mapped all 89 genes harboring de novo damaging mutations in OCD onto the GeNets Metanetwork v1.0 to determine whether they are functionally connected. Details about the databases and statistical comparisons are provided in Supplemental Methods.