The first four waves of data collection have been earlier described (Kaprio 2006). Based on these data, several sub-studies of selected pairs have been conducted, but this review will not cover those in detail as they are or will be the subject of separate reviews. See Naukkarinen et al (2012) for a review of the study of weight-discordant MZ pairs. There is an ongoing study of physical activity discordant pairs led by professor Urho Kujala (University of Jyväskylä), while results from our study of alcohol dependence discordant and concordant pairs have been reported (Latvala et al, 2011, Koskinen et al, 2011).