Interview participants described how TREC I's requirements to collaborate across disciplines, levels of analysis, and TREC I research centers had led them to develop new collaborations that would not have formed organically. These new collaborations brought together colleagues from different disciplines, departments, schools, and institutions, as well as community-based organizations and translational partners (e.g., local health departments). Participants reported that these collaborations had generated new TD research directions and informed new thinking on the translational applications of their work. Both of these developments were new, as many TREC I investigators had not worked on translational studies before. Participants anticipated that these new collaborations would continue even after TREC I funding had ended.