Descriptive statistics on the sample by genotype are shown in Table 1. Among the sample of 104 European-American youth, 30 adolescents (28.8%) carried the G allele [AG = 24% (n = 25), GG = 4.8% (n = 5)]; the remainder were homozygous for the A allele [71.2% (n = 74)].Allele frequencies were consistent with Hardy–Weinberg equilibrium (χ2 = 2.07, df = 1, p =.15).In terms of AUD diagnoses, 18 adolescents (17.31%) met diagnostic criteria either alcohol abuse [5.8% (n = 6)] or dependence (11.5% (n = 12)].The proportion of youth diagnosed with an AUD in this sample was comparable to prevalence rates reported for European-American youth (ages 12-17 years) in a large representative sample of adolescents in the U.S. (Wu et al., 2011).As illustrated in Table 1, case-control comparisons showed that the proportion of youth with an AUD significantly differed by genotype such that 33.3% of G allele carriers met criteria for an AUD compared to 10.8% of youth who were homozygous for the A allele(χ2 = 7.57, df = 1, p = .006). In addition, compared to youth who
