The current paper takes advantage of data from two generations of the SDPS to compare the cross-sectional and prospective relationships of different measures of the low LR to 2 outcomes most likely to be relatively closely linked to LR, maximum drinks per occasion, and the number of alcohol problems experienced. Hypothesis 1 states that for male probands, for whom both alcohol challenges and SRE data are available, both types of measures will correlate with alcohol outcomes. Similarly, for both probands and offspring, all four SRE scores will correlate with those two key outcomes. Hypothesis 2 predicts that, reflecting the longer time between the first 5 or so times of drinking in probands compared with younger subjects, the correlations between SRE-5 and both cross-sectional and prospective drinking parameters will be higher in the SDPS offspring than in the original probands. Hypothesis 3 predicts that, reflecting the focus of SRE-3 on the most recent LR values, SRE-3 will have higher correlations with current and future drinking maximum drinks and alcohol problems compared with the other SRE scores. In Hypothesis 4, because of