The Psychiatric GWAS Consortium (PGC) was formed in 2007 to conduct “mega-analysis” of individual genotype and phenotype data, and is described in detail elsewhere (Cross Disorder Phenotype Group of the Psychiatric GWAS Consortium, 2009, Psychiatric GWAS Consortium, 2009a, Psychiatric GWAS Consortium, 2009b). GWAS data for ADHD, autism, bipolar disorder, major depressive disorder, and schizophrenia from European subjects are being analyzed as of this writing in 9/2009. To our knowledge, this study of >59,000 independent cases and controls and >7,700 family trios will be the largest biological experiment conducted in psychiatry.
