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Chunk #11 — GWAS for Psychiatric Disorders

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Genome-wide association studies: a primer.
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Multiple GWAS for psychiatric disorders are published, in progress, or planned. The disorders include anorexia nervosa, attention-deficit hyperactivity disorder, autism, bipolar disorder, drug use disorders (smoking behavior and alcohol dependence), major depressive disorder, obsessive-compulsive disorder, and schizophrenia. There are > 50 primary samples, mostly in subjects of European ancestry but with increasing numbers of subjects of African and East Asian ancestry. Prominent examples of GWAS findings for psychiatric disorders are described in Table 2. This area is moving quickly, and additional findings are known to be in the publication pipeline.