Chunk #20 — Results — Kal7 is expressed in the major neuronal cell types in nucleus accumbens and dorsal striatum — Kal7 is the major Kalirin protein in the dorsal striatum and nucleus accumbens
To confirm the identity of the bands identified as Kal7 and ΔKal7, antiserum specific to the unique COOH-terminus of Kal7 was used (Figure 5, top right). Levels of both Kal7 and ΔKal7 were higher in cortex than in striatum or nucleus accumbens, with a clear signal for ΔKal7 detected only in cortex. As observed in the rat [26,28], levels of ΔKal7 protein were significantly lower than predicted based on utilization of the ΔKalrn promoter (Figure 4B).
