To ensure that the genotyped SNPs adequately covered the genes under consideration, linkage disequilibrium (LD) was computed using the program Haploview (Barrett et al., 2005). An independent evaluation was performed using the program Tagger (de Bakker et al., 2005) to calculate the fraction of all SNPs in each region analyzed by HapMap (with MAF > 0.10) that were in LD (r2≥ 0.80) with the SNPs we genotyped.
