As a variety of bioinformatics tools have been developed to obtain insights in GWAS results23–25, we compared the list of features available in FUMA with the features available in other tools, and describe these further below (Table 1).Table 1Feature comparison of bioinformatics tools and data sourcesToolsFormatGWAS summary statisticsLDFunctional consequences on genesRegulatory elementseQTLs3D chromatin interactionsPrioritize SNPsMap SNPs to genesGene expressionPathways and gene setsPrioritize genesVisualization LD calculation PLINKStxx Variant annotations ANNOVARStxxxx VEPStxxxx SCANWebxxxx ReglomeDBWebxxxx HaploRegWebxxxx Gene-based test/Gene-set analyses VEGASStxxx MAGMAStxxxx PascalStxxxx MAGENTAStxxxx INRICHStxxx DEPICTStxxxx Visualization tools LocusZoomSt/Webxx LocusTrackSt/Webxxx3D genome browserWebxx FUMA WebxxxxxxxxxxxxSt Standalone software, Web Web-based application
