Another suggestive association was at rs8059260 (P = 1.6 × 10−6, β = 0.017, SE = 0.004; MAF = 0.160; Supplementary Fig. 3), which is near the first exon of CLEC16A. Using the Genotype-Tissue Expression Portal (GTEx) database, we identified a cis- expression quantitative trait loci (eQTLs) for CLEC16A that co-localized with rs8059260 (r2 > 0.79; see Supplementary Table 7). We also found evidence of regulatory elements associated with rs8059260 using the RegulomeDB (Boyle et al. 2012; Supplementary Table 7).
