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Chunk #2 — RESULTS — Hippocampal glucocorticoid receptor expression

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Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.
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We examined the relationship between glucocorticoid receptor expression and psychiatric diagnoses (Table 1). Mood disorders and substance abuse disorders are risk factors for suicide and have been linked to alterations of glucocorticoid receptor expression12. There were no significant effects of psychopathology, even after controlling for childhood abuse status, on overall glucocorticoid receptor or glucocorticoid receptor 1F expression (P > 0.05).