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Chunk #26 — Results — Biometric Model Fitting: Substance Use Disorder — Univariate models

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Age at first use and later substance use disorder: Shared genetic and environmental pathways for nicotine, alcohol, and cannabis.
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Univariate model-fitting results are presented in Table S7 in supplemental materials and standardized full model estimates of A, C, and E for the full sample, men and women are presented in Table 3. Inspection reveals that: (1) additive genetic factors explained a significant proportion of the variation in all three symptom counts, (2) the pattern of estimates for ND was very similar across men and women, and (3) shared environmental influences were minimal for ND and AUD, but explained a modest (although non-significant) proportion of the variation in CUD (.11 [−.05, .28]).