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Chunk #1 — Introduction

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A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.
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The big five factors are openness to experience, conscientiousness, extraversion, agreeableness and neuroticism. Openness to experience is reflected in a strong intellectual curiosity and a preference for novelty and variety. Individuals scoring high on conscientiousness are characterized as being disciplined, organized and achievement-oriented. The extraversion dimension characterizes the tendency to be active, seek out stimulation and the company of others. Agreeableness evaluates the tendency to be helpful, cooperative and sympathetic towards others. Lastly, emotional stability, impulse control and anxiety are all components of the Neuroticism dimension.