Chunk #50 — Methods — Genotyping and imputation

Source

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

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MVP GWAS genotyping was performed using an Affymetrix Axiom Biobank Array with 686,693 markers. Subjects or SNPs with genotype call rate <0.9 or high heterozygosity were removed, leaving 353,948 subjects and 657,459 SNPs for imputation22.