lead SNPs in the 1000 Genomes data, and compared the LD in the 1000 Genomes data with LD (for the same combinations of SNPs) in the UKB data (Supplementary Data 4). None of these checks suggested genotyping errors of these SNPs. However, as the evidence for these loci was based on very few SNPs we decided to exclude them, and count the total number of unique genomic loci for all 12 items and the sum-score as 261–6 = 255.