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Chunk #41 — ONLINE METHODS — Association Analysis — Association / Meta-analysis

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Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
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The summary statistics from deCODE were combined with those from our primary GWAS dataset using an inverse variance-weighted fixed effects model. Similarly to the discovery meta-analysis (see above) we merged overlapping LD-clumps to a total of 287 distinct genomic regions (5 on the X-chromosome) with at least one genome-wide significant signal.