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Chunk #97 — Methods/Design — Analysis model 2C

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Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.
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Our broadest analysis will estimate allele frequencies among the cells of a 2×2 table defined by stress exposure and lifetime diagnosis of major depression, followed by a determination of whether there is evidence of a direct or interaction association between 5-HTTLPR variation and depression.