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Chunk #18 — Results

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Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians.
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For medical conditions related to alcoholism, the combined studies of alcoholics with alcoholic liver disease, cirrhosis (specifically), and (or) pancreatitis produced a strong association with P value of 2×10−28 (OR = 0.23 (0.18, 0.3)) with no evidence of significant heterogeneity (P = 0.5). The studies of alcoholic cirrhosis also showed strong association with P value of 6×10−19.