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Chunk #7 — Methods — Generation Scotland: Scottish Family Health Study

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Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort.
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Alcohol consumption was assessed using a pre‐clinical questionnaire. Participants were identified as current drinkers, former drinkers or never drinkers. Consumption was measured in self‐reported units of alcohol consumed in the previous week and converted into grams of alcohol/kg/week by multiplying units by 7.9 and dividing by the participant's weight (measured in the research clinic) in kilograms. All components of GS:SFHS have received ethical approval from the NHS Tayside Committee on Medical Research Ethics (REC Reference No. 05/S1401/89).