Blood samples were collected using standard operating procedures and stored at the Wellcome Trust Clinical Research Facility Genetics Core, Edinburgh (www.wtcrf.ed.ac.uk) where they were genotyped using the IlluminaHumanOmniExpressExome ‐8v1.0 BeadChip and Infinum chemistry (Gunderson 2009). The genotypes were then processed using the IlluminaGenomeStudio Analysis software v2011.1. The details of blood collection and DNA extraction are provided elsewhere (Smith et al. 2006).
