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Chunk #25 — Results — Study 2: clonidine effects on saccharin intake

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The α2-adrenergic receptor agonist, clonidine, reduces alcohol drinking in alcohol-preferring (P) rats.
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There was no significant difference in water intake between treatment groups on the pre-drug day. During the 3 treatment days, there was no significant effect of treatment or day and no treatment × day interaction effect on water intake. The 3-day average water intakes were 3.1 ± 0.7 mL/2 h for the saline-treated group and 5.2 ± 1.2 mL/2 h for the clonidine-treated group.