following assumptions: two-tailed P = 9.7 × 10−6 (Bonferroni correction for 5,151 SNPs), lifetime morbid risk of AN of 0.009 [Hudson et al., 2007], and a log additive genetic model. For the broad phenotype, All AN, (1,085 AN cases, 677 controls), the minimum detectible genotypic relative risks were 1.8, 1.5, and 1.5 for minor allele frequencies of 0.10, 0.25, and 0.40. For the AN with No Binge Eating phenotype, (687 cases, 677 controls), the minimum detectible genotypic relative risks were 1.9, 1.6, and 1.5 for minor allele frequencies of 0.10, 0.25, and 0.40. For the narrow phenotype, Restricting AN, (421 cases, 677 controls), the minimum detectible genotypic relative risks are 2.0, 1.7, and 1.6 for minor allele frequencies of 0.10, 0.25, and 0.40.
