Table II presents the 25 most significant SNPs from the association analyses conducted on the broadest definition of illness, that is, the All AN phenotype. The λ for All AN was 1.01, close to unity, which is consistent with a lack of stratification artifacts. The minimum p value using the trend test was 4.7 × 10−5, which corresponds to an FDR of 0.22, suggesting no significant differences between cases and controls. Table II also presents the p values and FDR for those top 25 SNPs from the analyses reported below for the AN with No Binge Eating and Restricting AN phenotypes for comparison. Figure 1a presents the QQ plot for this comparison. The QQ plot is based on P-values that correspond to the 1 degree-of-freedom Wald test on 5,151 autosomal SNPs by assuming an additive risk model. The observed values correspond closely to that expected by chance.
