Secondary outcomes included the change in severity of ADHD core symptoms based on parents' ratings for children and adolescents and self-reports for adults, clinical global functioning measured by the Clinical Global Impression–Improvement (CGI-I, clinicians' ratings), acceptability (ie, the proportion of participants who left the study for any reason), and change in weight and blood pressure. We assessed those outcomes available at the times closest to 12 weeks (primary endpoint), 26 weeks, and 52 weeks.