The dominant role of environmental influences in remission is consistent with the literature finding no association of familial history of AUD with remission (Dawson et al. 2007; Knop et al. 2007; Gilder et al. 2008) and stands in striking contrast to strong and coherent evidence for genetic influences on AUD (Kendler et al. 1994; Prescott et al. 1994, 1999; Heath et al. 1997; Prescott & Kendler, 1999; Knopik et al. 2004; Sartor et al. 2009, 2011). Genetic findings for AUD in the current study were broadly consistent with results reported previously for a narrower alcohol dependence phenotype for this sample (Knopik et al. 2004) and with a broadly defined alcohol use phenotype in a sample of US twins (Prescott & Kendler, 1999; Prescott et al. 1999). Shared environmental influences on AUD in male twins were detected in the bivariate analyses in the current study and before age 23 in a study of twins followed longitudinally (van Beek et al. 2012), but were not noted previously in reports of univariate genetic analysis (Heath et al. 1997; Prescott et al. 1999; Knopik
