To our knowledge, this is the first published study to examine the heritability of remission from AUD in a twin sample. Unlike previous studies that used familial AUD as a proxy for potential genetic influences on remission, the current study used a remission phenotype to test genetic influences on remission and also tested genetic and environmental influences shared with AUD. Environmental influences alone accounted for remission in men, with environments shared with the co-twin accounting for 37% of the variance. In women, environments unique to the individual accounted for 89% of influences on remission, with the remainder attributable to genetic effects associated with both AUD and remission. Variance common to AUD and remission had a negative influence on remission in men and women.
