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Chunk #15 — THE GENETIC BASIS OF VULNERABILITY TO ALCOHOLISM — The Neurobiology of Addiction: Dopamine Reward Circuitry and Interacting Stress Response Systems

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Genetic influences on the development of alcoholism.
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Genetic variation in neurobiological pathways, including stress-response systems, may influence vulnerability to the development of permanent neurological changes in response to heavy alcohol use. Likewise, genetic variation may determine increased vulnerability to relapse in response to stressors.