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Chunk #67 — Methods — Constructing Repository PGIs — Criterion for Inclusion in Repository

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Resource profile and user guide of the Polygenic Index Repository.
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We find that our criterion results in 47 phenotypes with at least one PGI in the Repository (see Figure 2). For 12 phenotypes, our procedure results in the release of a single-trait PGI but no multi-trait PGI; these are the phenotypes with no supplementary phenotypes. For 11 other phenotypes, our procedure results in the release of a multi-trait PGI but no single-trait PGI; these are typically phenotypes without large GWASs but for which we have multiple supplementary phenotypes with large GWASs. Finally, our procedure yields 24 phenotypes with both single- and multi-trait PGIs that satisfy our inclusion criterion (Table 1) and 6 phenotypes for which neither PGI qualifies.